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What Is Roxanol? : Buy Roxanol Pills Online

Roxanol (morphine sulfate) is a highly concentrated solution of the narcotic analgesic morphine sulfate for oral administration used for the treatment of severe, chronic pain.

What Are Side Effects of Roxanol?

Side effects of Roxanol include:

  • constipation,
  • nausea,
  • vomiting,
  • stomach pain,
  • diarrhea,
  • loss of appetite,
  • weight loss,
  • headache,
  • dizziness,
  • spinning sensation,
  • anxiety,
  • flushing (warmth, redness, or tingly feeling),
  • memory problems, or
  • sleep problems (insomnia or strange dreams).

Dosage for Roxanol

The usual adult oral dose of Roxanol is 10 to 30 mg every 4 hours or as directed by physician.

What Drugs, Substances, or Supplements Interact with Roxanol? : Buy Roxanol Pills Online

Roxanol may interact with alcohol, other narcotic pain medications, antidepressants, sedatives, tranquilizers, sleeping pills, muscle relaxers, other medicines that can make you sleepy or slow your breathing, cimetidine, buprenorphine, butorphanol, nalbuphine, pentazocine, or diuretics (water pills). Tell your doctor all medications and supplements you use.

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It is not known whether morphine can cause fetal harm when administered to a pregnant woman, so morphine should be given to a pregnant woman only if clearly needed.

Morphine readily crosses the placental barrier and if administered during labor, may lead to respiratory depression in the neonate.

Morphine has been detected in human milk. For this reason, caution should be exercised when morphine is administered to a breastfeeding woman.

Additional Information

Our Roxanol Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

Indications & Dosage

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Morphine is indicated for the relief of severe acute and severe chronic pain.


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Roxanol (Morphine Sulfate 20 mg/mL) is a HIGHLY CONCENTRATED solution of Morphine Sulfate for Oral Administration.

Error in dosage or confusion between milligrams (mg) of morphine and milliliters (mL) of solution may cause significant over-dosage.

Dosing instructions should be clearly pre-scribed in milligrams (mg) of morphine and milliliters (mL) of solution. VERIFY CORRECT DOSE AND VOLUME BEFORE ADMINISTRATION TO PATIENT.

Usual Adult Oral Dose : Buy Roxanol Pills Online

10 to 30 mg every 4 hours or as directed by physician. Dosage is a patient dependent variable, therefore increased dosage may be required to achieve adequate analgesia.

For control of severe, chronic pain in patients with certain terminal diseases, this drug should be administered on a regularly scheduled basis, every 4 hours, at the lowest dosage level that will achieve adequate analgesia.

Note: Medication may suppress respiration in the elderly, the very ill, and those patients with respiratory problems, therefore lower doses may be required.

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During the first two to three days of effective pain relief, the patient may sleep for many hours. This can be misinterpreted as the effect of excessive analgesic dosing rather than the first sign of relief in a pain exhausted patient.

The dose, therefore, should be maintained for at least three days before reduction, if respiratory activity and other vitals signs are adequate.

Following successful relief of severe pain, periodic attempts to reduce the narcotic dose should be made. Smaller doses or complete discontinuation of the narcotic analgesic may become feasible due to a physiologic change or the improved mental state of the patient.

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Morphine Sulfate (Immediate Release)
Oral Solution (Concentrate)

20 mg per mL

NDC 66479-560-03: Bottles of 30 mL with calibrated dropper.

NDC 66479-560-12: Bottles of 120 mL with calibrated dropper.

NDC 66479-560-24: Bottles of 240 mL with calibrated spoon.

Store at 25°C (77°F);excursions are permitted to 15°-30°C (59°-86°F) [See USP Controlled Room Temperature]

Side Effects & Drug Interactions

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The most frequently observed adverse reactions include lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. These effects seem to be more prominent in ambulatory patients and in those who are suffering severe pain.

In such individuals, lower doses are available. Some adverse reactions may be alleviated in the ambulatory patient if he lies down.

Other adverse reactions include the following : Buy Roxanol Pills Online

Central Nervous System: Euphoriadysphoria, weakness, headache, insomnia, agitation, disorientation, and visual disturbances.

Gastrointestinal: Dry mouthanorexia, constipation, and biliary tract spasm.

Cardiovascular: Flushing of the face, bradycardia, palpitation, faintness and syncope.

Allergic: Pruritusurticaria, other skin rashes, edema, and, rarely hemorrhagic urticaria.

Treatment of the most frequent adverse reactions


Ample intake of water or other liquids should be encouraged. Concomitant administration of a stool softener and a peristaltic stimulant with the narcotic analgesic can be an effective preventive measure for those patients in need of therapeutics.

If elimination does not occur for two days, an enema should be administered to prevent impaction.

In the event diarrhea occurs, seepage around fecal impaction is a possible cause to consider before antidiarrheal measures are employed.

Nausea and Vomiting

Phenothiazines and antihistamines can be effective treatments of nausea of the medullary and vestibular sources respectively. However, these drugs may potentiate the side effects of the narcotic or the antinauseant.

Drowsiness (sedation)

Once pain control is achieved, undesirable sedation can be minimized by titrating the dosage to a level that just maintains a tolerable pain or pain free state.

Drug Abuse And Dependence : Buy Roxanol Pills Online

Morphine Sulfate, a narcotic, is a Schedule II controlled substance under the Federal Controlled Substance Act. As with other narcotics, some patients may develop a physical and psychological dependence on morphine.

They may increase dosage without consulting a physician and subsequently may develop a physical dependence on the drug.

In such cases, abrupt discontinuance may precipitate typical withdrawal symptoms, including convulsions. Therefore the drug should be withdrawn gradually from any patient known to be taking excessive dosages over a long period of time.

In treating the terminally ill patient the benefit of pain relief may outweigh the possibility of drug dependence.

The chance of drug dependence is substantially reduced when the patient is placed on scheduled narcotic programs instead of a “pain to relief-of-pain” cycle typical of a PRN regimen.

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Generally, effects of morphine may be potentiated by alkalizing agents and antagonized by acidifying agents. Analgesic effect of morphine is potentiated by chlorpromazine and methocarbamol.

CNS depressants such as anaesthetics, hypnotics, barbiturates, phenothiazines, chloral hydrate, glutethimide, sedatives, MAO inhibitors (including procarbazine hydro-chloride), antihistamines, β-blockers (propranolol), alcohol, furazolidone and other narcotics may enhance the depressant effects of morphine.

Morphine may increase anticoagulant< activity of coumarin and other anticoagulants.

Warnings & Precautions

WARNINGS : Buy Roxanol Pills Online

Morphine can cause tolerance, psychological and physical dependence. Withdrawal will occur on abrupt discontinuation or administration of a narcotic antagonist.

Interaction with Other Central Nervous System Depressants

Morphine should be used with caution and in reduced dosage in patients who are concurrently receiving other narcotic analgesics, general anesthetics, phenothiazines, other tranquilizers, sedative-hypnotics, tricyclic antidepressants, and other CNS depressants (including alcohol). Respiratory depressionhypotension, and profound sedation or coma may result.

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Head Injury and Increased Intracranial Pressure

The respiratory depressant effects of morphine and its capacity to elevate cerebrospinal-fluid pressure may be markedly exaggerated in the presence of increased intracranial pressure.

Furthermore, narcotics produce side effects that may obscure the clinical course of patients with head injuries. In such patients, morphine must be used with caution and only if it is deemed essential.

Asthma and Other Respiratory Conditions

Morphine should be used with caution in patients having an acute asthmatic attack, in those with chronic obstructive pulmonary disease or cor pulmonale, and in individuals with a substantially decreased respiratory re-serve, preexisting respiratory depression, hypoxia, or hypercapnia.

In such patients, even usual therapeutic doses of narcotics may decrease respiratory drive while simultaneously increasing airway resistance to the point of apnea.

Hypotensive Effect

The administration of morphine may result in severe hypotension in an individual whose ability to maintain his blood pressure has already been compromised by a depleted blood volume or concurrent administration of such drugs as the phenothiazines or certain anesthetics.

Special-Risk Patients

Morphine should be given with caution and the initial dose should be reduced in certain patients, such as the elderly or debilitated and those with severe impairment of hepatic or renal function, hypothyroidism, Addison’s disease, prostatic hy-pertrophy, or urethral stricture.

Acute Abdominal Conditions

The administration of morphine or other narcotics may obscure the diagnosis or clinical course in patients with acute abdominal conditions.


Long-term studies to determine the carcinogenic and mutagenic potential of morphine are not available.


Teratogenic Effects

Pregnancy Category C

Animal reproduction studies have not been conducted with morphine. It is also not known whether morphine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.

Morphine should be given to a pregnant woman only if clearly needed.

Labor and Delivery

Morphine readily crosses the placental barrier and if administered during labor, may lead to respiratory depression in the neonate.

Nursing Mothers

Morphine has been detected in human milk. For this reason, caution should be exercised when morphine is administered to a nursing woman.

Pediatric Usage

Safety and effectiveness in children have not been established.

Overdose & Contraindications


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. In severe overdosage, apnea, circulatory collapse, cardiac arrest and death may occur.


In all cases of suspected overdosage, call 800-222-1222 to obtain the most up-to-date information about the treatment of overdose. By calling this number, you will be automatically connected to your local Poison Control Center.

Primary attention should be given to the re-establishment of adequate respiratory exchange through provision of a patent airway and the institution of assisted or controlled ventilation.

The narcotic antagonist naloxone is a specific antidote against respiratory depression which may result from overdosage or unusual sensitivity to narcotics, including morphine.


An antagonist should not be administered in the absence of clinically significant respiratory or cardio-vascular depression.

Oxygen, intravenous fluids, vasopressors and other supportive measures should be employed as indicated.

Gastric emptying may be useful in removing unabsorbed drug.

CONTRAINDICATIONS : Buy Roxanol Pills Online

Hypersensitivity to morphine; respiratory insufficiency or depression; severe CNS depression;attack of bronchial asthmaheart failure secondary to chronic lung disease;cardiac arrhythmias;increased intracranial or cerebrospinal pressure;head injuries;brain tumor; acute alcoholismdelirium tremens; convulsive disorders; after biliary tract surgery; suspected surgical abdomen; surgical anastomosis; concomitantly with MAO inhibitors or within 14 days of such treatment.

Clinical Pharmacology

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The major effects of morphine are on the central nervous system and the bowel. Opioids act as agonists, interacting with stereospecific and saturable binding sites or receptors in the brain and other tissues.

Morphine is about two-thirds absorbed from the gastrointestinal tract with the maximum analgesic ef-fect occurring 60 minutes post administration.

Medication Guide

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Use in Ambulatory Patients

Morphine may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a car or operating machinery.

The patient should be cautioned accordingly.

Morphine, like other narcotics, may product orthos-tatic hypotension in ambulatory patients.

Patients should be cautioned about the combined effects of alcohol or other central nervous system depressants with morphine.

How to use Roxanol Solution :

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Read the Medication Guide provided by your pharmacist before you start taking morphine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor. You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible).

If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon.

Do not use a household spoon because you may not get the correct dose. Ask your pharmacist or doctor if you are not sure how to check or measure the dose.

The dosage is based on your medical condition and response to treatment. Do not increase your dose, take the medication more often, or take it for a longer time than prescribed. Properly stop the medication when so directed.

Pain medications work best if they are used when the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.

If you have ongoing pain (such as due to cancer), your doctor may direct you to also take long-acting opioid medications. In that case, this medication might be used for sudden (breakthrough) pain only as needed.

Other pain relievers (such as acetaminophenibuprofen) may also be prescribed with this medication. Ask your doctor or pharmacist about using morphine safely with other drugs.

Suddenly stopping this medication may cause withdrawal, especially if you have used it for a long time or in high doses.

To prevent withdrawal, your doctor may lower your dose slowly.

Tell your doctor or pharmacist right away if you have any withdrawal symptoms such as restlessness, mental/mood changes (including anxiety, trouble sleeping, thoughts of suicide), watering eyesrunny nose, nausea, diarrheasweating, muscle aches, or sudden changes in behavior.

When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

 Uses of Roxanol : Buy Roxanol Pills Online

Roxanol is primarily used to alleviate pain that cannot be effectively managed with milder pain medications. It is often prescribed for:

  • Post-operative pain
  • Chronic pain due to cancer or other severe medical conditions
  • Pain management in palliative care

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Research the Online Pharmacy

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Always ensure you have a valid prescription from a licensed healthcare professional before attempting to buy Roxanol online. Reputable online pharmacies will require a prescription to dispense the medication, as it is a controlled substance.

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 Potential Side Effects of Roxanol

As with any medication, Roxanol may cause side effects, ranging from mild to severe. Common side effects may include nausea, constipation, dizziness, and drowsiness.

However, some individuals may experience more serious side effects, such as respiratory depression or allergic reactions.

 Seeking Medical Assistance

If you experience severe side effects or an allergic reaction to Roxanol, seek immediate medical attention. Contact your healthcare provider or local emergency services for prompt assistance.

 Frequently Asked Questions (FAQs)

Can I buy Roxanol without a prescription online?

A: No, Roxanol is a prescription medication, and reputable online pharmacies will require a valid prescription before dispensing it.

5.2 Q: How should I store Roxanol pills?

A: Store Roxanol pills at room temperature, away from moisture and heat. Keep them out of reach of children and pets.

5.3 Q: Are there any potential drug interactions with Roxanol?

A: Yes, Roxanol may interact with certain medications. It is essential to inform your healthcare provider about all the medications you are currently taking to avoid potential interactions.

5.4 Q: Can I take Roxanol during pregnancy?

It may pose risks to the unborn baby, and your doctor will weigh the benefits and risks before recommending its use.

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A: Roxanol belongs to the opioid class of medications, and prolonged use may lead to physical dependence. It is crucial to take the medication as prescribed by your doctor to minimize the risk of addiction.

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Always have a valid prescription and choose reputable online pharmacies for a secure transaction. If used as prescribed and with appropriate precautions, Roxanol can effectively alleviate pain and improve the quality of life for individuals with severe pain conditions.

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